DBC2 belongs to RAS-BTB family. (A gene family is a group of genes with similar structure.)
RAS proteins are known to play an important role in signal transduction. They are also demonstrated to be responsible for cancer development. BTB domains are protein-protein interacting modules. However, the structure of DBC2 is distincitive from other BTB proteins. Cellular functions of DBC2 remain unclear.
Human DBC2 sequences are listed below.
genomic sequence (AF315385)
|Genomic sequencing was completed in collaboration with Dr. McCombie of Cold Spring Harbor Laboratory.|